Flowproof MCP vs ChatSpatial

In-depth architectural comparison of the Flowproof MCP and ChatSpatial MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

Which MCP Server Should You Choose?

Choose Flowproof MCP when:

• You need dedicated capabilities in the Biology, Medicine and Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: list_pipelines, describe_pipeline, run_pipeline.

Explore Flowproof MCP Details

Choose ChatSpatial when:

• You need dedicated capabilities in the Biology, Medicine and Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: API Key required (Free / Open Source).
• You have access to required keys: CHATSPATIAL_API_KEY, CHATSPATIAL_CONFIG_PATH, CHATSPATIAL_HTTP_PORT, CHATSPATIAL_LOG_LEVEL.
• Primary tools included: 20 MCP tools exposing 66 spatial transcriptomics methods, Schema-enforced orchestration for reproducible workflows, Supports 10x Visium, Xenium, Slide-seq v2, MERFISH, seqFISH data.

Feature & Specification Comparison

Specification	Flowproof MCP ajibadedapo Biology, Medicine and Bioinformatics	ChatSpatial cafferychen777 Biology, Medicine and Bioinformatics
Summary	Run reproducible bioinformatics pipelines (Nextflow) from an AI assistant, with verifiable Workflow Run RO-Crate provenance (container digests, tool versions, input/output checksums). pip install flowproof-mcp	MCP server for spatial transcriptomics analysis with 60+ integrated methods covering cell annotation, deconvolution, spatial statistics, and visualization.
Category & Scope

Tools & Capabilities Breakdown

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

{
  "mcpServers": {
    "ajibadedapo-flowproof-mcp": {
      "command": "uvx",
      "args": [
        "flowproof-mcp"
      ]
    }
  }
}

{
  "mcpServers": {
    "cafferychen777-chatspatial": {
      "command": "uvx",
      "args": [
        "--from"
      ],
      "env": {
        "CHATSPATIAL_API_KEY": "YOUR_CHATSPATIAL_API_KEY_HERE",
        "CHATSPATIAL_CONFIG_PATH": "YOUR_CHATSPATIAL_CONFIG_PATH_HERE",
        "CHATSPATIAL_HTTP_PORT": "YOUR_CHATSPATIAL_HTTP_PORT_HERE",
        "CHATSPATIAL_LOG_LEVEL": "YOUR_CHATSPATIAL_LOG_LEVEL_HERE"
      }
    }
  }
}

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