In-depth architectural comparison of the Decoder 3am MCP and Heor Agent MCP MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.
At a Glance & Executive Verdict
Decoder 3am MCP
Biology, Medicine and Bioinformatics · Local stdio
Quality: 52/100 (Good) | Auth: No auth required
Heor Agent MCP
Biology, Medicine and Bioinformatics · Local stdio
Quality: 61/100 (Good) | Auth: No auth required
Verdict Summary: Choose Decoder 3am MCP if you need specialized Biology, Medicine and Bioinformatics tools running via a local process. Choose Heor Agent MCP if your workspace requires Biology, Medicine and Bioinformatics integration with local subprocess execution. Both servers can be configured concurrently in your client's mcpServers manifest.
Which MCP Server Should You Choose?
Choose Decoder 3am MCP when:
You need dedicated capabilities in the Biology, Medicine and Bioinformatics domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
Sleep disruption cause classifier using The Longevity Vault's 5-cause framework. Identifies the biological mechanism behind 3am wakeups from symptom descriptions, with tracked links to the full interactive 3AM Decoder.
HEOR (Health Economics and Outcomes Research) MCP server with 7 tools for literature search across 41 medical data sources (PubMed, NICE, CADTH, ICER, etc.), cost-effectiveness modeling (Markov/PartSA/PSA), and HTA dossier preparation for pharmaceutical and biotech teams.
Category & Scope
Tools & Capabilities Breakdown
Decoder 3am MCP Tools (4)
classify_sleep_cause
Classify the likely primary cause of sleep disruption from a symptom description.
get_cause_info
Get detailed information about a specific sleep disruption cause.
list_causes
List all 5 sleep disruption causes with summaries.
get_decoder_url
Get a tracked URL to the full interactive 3AM Decoder.
Heor Agent MCP Tools (17)
literature_search
Search 44 data sources with a full PRISMA-style audit trail
Ready-to-Paste Client Configurations
Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).
Decoder 3am MCP is categorized under Biology, Medicine and Bioinformatics and uses a local stdio subprocess. In contrast, Heor Agent MCP belongs to Biology, Medicine and Bioinformatics using local stdio subprocess. Select Decoder 3am MCP when you need capabilities focused on biology, medicine and bioinformatics and Heor Agent MCP when you require tools for biology, medicine and bioinformatics.
PICO-based relevance scoring and study design classification
risk_of_bias
Cochrane RoB 2 / ROBINS-I / AMSTAR-2 with GRADE RoB domain summary
evidence_network
Build treatment comparison network and assess NMA feasibility
evidence_indirect
Bucher and frequentist NMA with **automatic consistency check** vs direct h2h evidence (NICE DSU TSD 18)
population_adjusted_comparison
MAIC and STC for population-adjusted indirect comparisons
survival_fitting
Fit 5 parametric distributions to KM data (NICE DSU TSD 14)
itc_feasibility
Assess the 3-assumption ITC framework and recommend Bucher / NMA / MAIC / STC / ML-NMR
cost_effectiveness_model
Markov / PartSA / decision-tree CEA with PSA, OWSA, CEAC, EVPI, EVPPI; QALY + evLYG support
budget_impact_model
ISPOR-compliant BIA with year-by-year output and treatment-displacement modelling
hta_dossier
Draft submissions for NICE, EMA, FDA, IQWiG, HAS, and EU JCA — GRADE table uses structured RoB when `rob_results` passed; **inconsistency uses I² when `heterogeneity_per_outcome` passed**; **GRADE upgrading (Guyatt 2011) supported via `upgrading_per_outcome`