Mygene Info vs Rcsb Pdb

In-depth architectural comparison of the Mygene Info and Rcsb Pdb MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

Which MCP Server Should You Choose?

Choose Mygene Info when:

• You need dedicated capabilities in the Biology & Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: Full-text gene queries, Single-gene annotation retrieval, Batch identifier lookups.

Explore Mygene Info Details

Choose Rcsb Pdb when:

• You need dedicated capabilities in the Biology & Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: Text search across RCSB PDB, Full structure entry records, Polymer entity metadata.

Explore Rcsb Pdb Details

Feature & Specification Comparison

Specification	Mygene Info Biology & Bioinformatics	Rcsb Pdb Biology & Bioinformatics
Summary	MyGene.info — gene annotation joining NCBI/Ensembl/UniProt/KEGG/OMIM	RCSB PDB MCP — experimentally determined macromolecular structures.
Category & Scope	Biology & Bioinformatics	Biology & Bioinformatics
Quality signal	39/100 (Fair)	41/100 (Fair)
Transport Protocol	Local Subprocess (stdio)	Local Subprocess (stdio)
Auth Requirement	No auth required	No auth required
Pricing Model	Free / Open Source	Free / Open Source
Required Env Vars	None required	None required
Compatible Clients	Claude DesktopCursorWindsurfClineVS Code	Claude DesktopCursorWindsurfClineVS Code
Install path signal	npx · high	npx · high
Engagement & Health	0 views 0 copies 0 upvotes 0 stars	0 views 0 copies 0 upvotes 0 stars
Verified / Official	Community Listing	Community Listing
Open full listing	View Mygene Info Listing	View Rcsb Pdb Listing

Tools & Capabilities Breakdown

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

{
  "mcpServers": {
    "mygene-info": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-mygene-info"
      ]
    }
  }
}

{
  "mcpServers": {
    "rcsb-pdb": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-rcsb-pdb"
      ]
    }
  }
}

Related MCP Server Comparisons