Mygene Info vs Opentreeoflife

In-depth architectural comparison of the Mygene Info and Opentreeoflife MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

Which MCP Server Should You Choose?

Choose Mygene Info when:

• You need dedicated capabilities in the Biology & Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: Full-text gene queries, Single-gene annotation retrieval, Batch identifier lookups.

Explore Mygene Info Details

Choose Opentreeoflife when:

• You need dedicated capabilities in the Biology & Bioinformatics domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: match_names, taxon_info, common_ancestor.

Explore Opentreeoflife Details

Feature & Specification Comparison

Specification	Mygene Info Biology & Bioinformatics	Opentreeoflife Biology & Bioinformatics
Summary	MyGene.info — gene annotation joining NCBI/Ensembl/UniProt/KEGG/OMIM	Open Tree of Life MCP.
Category & Scope	Biology & Bioinformatics	Biology & Bioinformatics
Quality signal

Tools & Capabilities Breakdown

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

{
  "mcpServers": {
    "mygene-info": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-mygene-info"
      ]
    }
  }
}

{
  "mcpServers": {
    "opentreeoflife": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-opentreeoflife"
      ]
    }
  }
}

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