Side-by-Side Model Context Protocol Comparison
Interpro vs Alphafold
In-depth architectural comparison of the Interpro and Alphafold MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.
At a Glance & Executive Verdict
Interpro
Biology & Bioinformatics · Local stdio
Quality: 27/100 (Emerging) | Auth: No auth required
Alphafold
Biology & Bioinformatics · Remote HTTP/SSE
Quality: 48/100 (Fair) | Auth: No auth required
Verdict Summary: Choose Interpro if you need specialized Biology & Bioinformatics tools running via a local process. Choose Alphafold if your workspace requires Biology & Bioinformatics integration with remote web transport. Both servers can be configured concurrently in your client's
mcpServers manifest.Which MCP Server Should You Choose?
I
Choose Interpro when:
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer local stdio subprocess transport architecture.
- Your security boundary fits: No auth required (Free / Open Source).
A
Choose Alphafold when:
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer remote streaming HTTP/SSE transport architecture.
- Your security boundary fits: No auth required (Free / Open Source).
- Primary tools included: prediction.
Feature & Specification Comparison
Tools & Capabilities Breakdown
Interpro Tools (0)
No explicit tool names declared in metadata yet. Check project README on main listing page.
Alphafold Tools (1)
prediction
Ready-to-Paste Client Configurations
Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).
Interpro Configuration
Alphafold Configuration
Frequently Asked Questions
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