Hpo Api vs Molecare MCP
A side-by-side look at the Hpo Api and Molecare MCP MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.
Verdict: choose Hpo Api for biology & bioinformatics work as a local process; choose Molecare MCP for biology & bioinformatics as a local process. You can also run both side by side in one mcpServers block.
Which MCP server should you choose?
Choose Hpo Api when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer a local stdio subprocess transport.
- You want tools like
term, search, term_children.
Choose Molecare MCP when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer a local stdio subprocess transport.
- You want tools like
get_user_moles, get_mole_analysis, get_mole_changes.
Feature & specification comparison
Rows where the two servers differ are marked.
| Spec | ||
|---|---|---|
| Category | Biology & Bioinformatics | Biology & Bioinformatics |
| Quality signal | 60/100 · Good | 59/100 · Good |
| Install command | Confirmed | Confirmed |
| Transport | Local subprocess (stdio) | Local subprocess (stdio) |
| Auth | Not declared | Not declared |
| Pricing | Not declared | Not declared |
| Required env vars | None listed | None listed |
| Verified owner | Community listing | Community listing |
| GitHub stars | 0 | 4 |
| Directory activity | 3 views 0 installs 0 upvotes | 2 views 0 installs 0 upvotes |
| Tools | 7 | 14 |
| Full listing | View Hpo Api | View Molecare MCP |
Tools & capabilities
Hpo Api tools 7
term"What does HP:[N] mean" / "look up HPO phenotype [ID]" — fetch a single Human Phenotype Ontology (HPO) term by ID. HPO is the standard ontology for clinical phenotypes used in rare-disease research. Returns label, definition, synonyms, cross-references. Example ID: HP:0001250 (Seizure).search"HPO term for [symptom]" / "phenotype code for [clinical sign]" / "find HPO IDs about [feature]" / "what's the HPO for seizures / autism / short stature" — text search the Human Phenotype Ontology (HPO). Returns ranked terms with HP: IDs. Use to map clinical descriptions to standard ontology terms for rare-disease workups, genomics, or clinical phenotype databases.term_children"More specific HPO phenotypes under [HP:N]" / "child terms of [phenotype]" — direct children of an HPO term in the ontology graph. Use to narrow from a general phenotype (e.g. "Abnormality of the nervous system") to specifics (seizures, ataxia, etc).term_parents"What broader phenotype is [HP:N] under" / "parent term of [HPO ID]" — direct parents of an HPO term in the ontology graph. Use to walk up to a more general phenotype class.term_descendants"All phenotypes under [HP:N]" / "full subtree of [HPO term]" — transitive descendants (children, grandchildren, …) of an HPO term. Use for exhaustive coverage (e.g. "every cardiac phenotype" via descendants of HP:0001626).gene_diseases"What diseases is gene [NCBIGene:N] associated with" / "diseases linked to gene [X]" / "TP53 disease associations" — fetch diseases associated with a gene ID (NCBIGene:N format). Use for gene-to-disease lookups in rare-disease research, variant prioritization. Example ID: NCBIGene:7157 (TP53).disease_phenotypes"What symptoms / clinical features does [disease] cause" / "HPO phenotypes for [OMIM N]" / "clinical signs of [rare disease]" — list HPO phenotype terms for a disease ID (OMIM:N, ORPHA:N, or MONDO:N format). Use to enumerate clinical features of rare diseases. Example ID: OMIM:154700 (Marfan syndrome).
Molecare MCP tools 14
get_user_molesList a user's recorded moles and last photo dates. Educational records only — not a risk ranking.get_mole_analysisReturn recorded ABCDE feature measurements for a mole. Educational only — not a diagnosis or risk level.get_mole_changesReturn recorded appearance changes for a mole over time. Observations only — not a trend verdict.get_user_risk_factorsList named educational skin-health factors on a user profile. Does not calculate a risk score.search_medical_infoSearch the medical knowledge base for skin health information. Use this to provide accurate educational content about skin conditions, ABCDE criteria, and prevention tips.compare_molesCompare two recorded mole photos. Reports observed differences only — not a diagnosis.lookup_medical_conceptLook up a medical concept by SNOMED CT code. Returns detailed information about skin conditions including severity and category. Use this to provide accurate medical terminology.search_medical_conceptsSearch for medical concepts by name or description. Returns matching SNOMED CT concepts for dermatology conditions.get_condition_progressionGet information about how a skin condition can progress. Shows potential progression paths (e.g., dysplastic nevus to melanoma).map_snomed_to_icd10Map a SNOMED CT code to ICD-10 diagnosis codes. Useful for understanding official diagnosis classifications.get_condition_risk_factorsGet risk factors associated with a specific condition. Returns factors like family history, skin type, UV exposure.assess_risk_from_factorsDescribe named educational skin-health factors from a list of factor IDs. Does not calculate a risk score or recommend urgency.- +2 more on the listing page
Ready-to-paste client configs
Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.
Hpo Api
{
"mcpServers": {
"hpo-api": {
"command": "npx",
"args": [
"-y",
"@pipeworx/mcp-hpo-api"
]
}
}
}
Molecare MCP
{
"mcpServers": {
"molecare-mcp": {
"command": "npx",
"args": [
"-y",
"molecare-mcp"
]
}
}
}
Frequently asked questions
Hpo Api is categorized under Biology & Bioinformatics and uses a local stdio subprocess. Molecare MCP belongs to Biology & Bioinformatics and uses a local stdio subprocess. Pick Hpo Api for biology & bioinformatics work and Molecare MCP for biology & bioinformatics.
Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client.
Hpo Api has no declared pricing — check the project's own site. Molecare MCP has no declared pricing — check the project's own site. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.
Yes. MCP clients support multiple servers: add hpo-api and molecare-mcp as separate keys in the same mcpServers object, and your assistant will call tools from either one.
On AllMCPs, Hpo Api has a quality signal of 60/100 (Good) with 3 views, 0 installs and 0 GitHub stars. Molecare MCP has 59/100 (Good) with 2 views, 0 installs and 4 GitHub stars.