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Biology & Bioinformatics• MCP Alternatives Guide

Best Alternatives to Hpo Api

Looking for an alternative to Hpo Api? Whether you need a different runtime environment, custom authentication support, or alternative API integrations in the Biology & Bioinformatics ecosystem, we have cataloged and compared the top alternative MCP servers below.

Browse all Biology & Bioinformatics servers →View Hpo Api Specs →
Hpo Api logo
Target Reference Server

Hpo Api Overview

Hpo Api MCP server exposes Human Phenotype Ontology terms and gene or disease annotations through MCP tools. It reads from the newer HPO REST API and falls back to the older HPO endpoint when needed. Use it to search clinical phenotype concepts, traverse HPO hierarchies, or connect genes and diseases to phenotype data. It supports a hosted gateway endpoint, direct HTTP calls, and a local keyless stdio package.

Primary Use Cases for Hpo Api:
  • Search HPO terms from clinical phenotype descriptions
  • Traverse parent, child, and descendant relationships
  • Find diseases associated with an NCBIGene identifier
  • Retrieve phenotypes annotated to an OMIM, ORPHA, or MONDO disease

Specification Matrix: Hpo Api vs Alternatives

Direct comparison of key metrics, runtimes, authentication methods, and community popularity.

Server NameRuntimeAuthPricingGitHub StarsDownloadsAction
Hpo Api logoHpo Api (Target)
npx————Current
Medical Terminologies MCP logoMedical Terminologies MCPnpxAPI keyFree15—Compare →
Myatriumhealth MCP logoMyatriumhealth MCPnpx—Free1—Compare →
ChemCP logoChemCPnpx——2—Compare →
Candor logoCandornpx——1—Compare →
Taiwan Health MCP logoTaiwan Health MCP—No auth requiredFree167—Compare →
Medplum MCP logoMedplum MCP———2,760—Compare →
Mirobody logoMirobody——Bring your own API key (usage-based cost)1,388—Compare →
Filesystem logoFilesystemnpxNo auth requiredFree91,512—Compare →
Webclaw logoWebclawnpxNo auth requiredFree2,3862Compare →
Firecrawl MCP Server logoFirecrawl MCP ServernpxAPI keyFreemium7,673—Compare →
Next Devtools MCP logoNext Devtools MCPnpxNo auth requiredFree832—Compare →
Hindsight logoHindsightnpxAPI keyFree53,003—Compare →

Detailed Evaluation of Hpo Api Alternatives

Medical Terminologies MCP logo

Medical Terminologies MCP

Runtime: npxBiology & Bioinformatics

Searches, validates, and cross-references ICD, LOINC, RxNorm, MeSH, ATC, and Brazilian CID-10 terminology data.

Key Features:
ICD-11 search, lookup, hierarchy, and postcoordination
LOINC, RxNorm, MeSH, ATC, and CID-10 tools
ICD-10 to ICD-11 transition mapping
Myatriumhealth MCP logo

Myatriumhealth MCP

Runtime: npxBiology & Bioinformatics

Read MyAtriumHealth records, manage patient context, authenticate with MFA, and reply to Message Center conversations through MCP.

Key Features:
MyAtriumHealth health-record queries
Browser-bridge or server-side authentication
MFA verification workflow
ChemCP logo

ChemCP

Runtime: npxBiology & Bioinformatics

Render interactive 2D molecular structures and computed properties from SMILES with RDKit.js inside MCP-compatible chat hosts.

Key Features:
2D structure rendering from SMILES
RDKit.js-based molecule parsing
Computed molecular descriptors
Candor logo

Candor

Runtime: npxBiology & Bioinformatics

Analyzes TypeScript function effects and exposes report queries for agent-assisted code review.

Key Features:
Per-function TypeScript effect analysis
Transitive call-graph queries
Network, filesystem, database, execution, environment, and clock effects
Taiwan Health MCP logo

Taiwan Health MCP

Runtime not confirmedBiology & Bioinformatics

Connects AI agents to Taiwan healthcare terminology, FHIR R4 services, TFDA drug data, lab references, and deterministic clinical calculators.

Key Features:
ICD-10-CM and ICD-10-PCS search and hierarchy browsing
SNOMED CT search, relationships, and ICD-10 mapping
LOINC discovery and lab-result interpretation
Medplum MCP logo

Medplum MCP

Runtime not confirmedBiology & Bioinformatics

Access and manage FHIR healthcare data in Medplum through MCP.

Key Features:
Accesses Medplum-hosted FHIR data
Manages healthcare records through Medplum
Uses Medplum’s FHIR-based API
Mirobody logo

Mirobody

Runtime not confirmedBiology & Bioinformatics

Self-hosted health data engine with an MCP server for standardizing, querying, and tracing lab, wearable, and genetic records.

Key Features:
Built-in MCP server
Lab, wearable, genetic, and Apple Health data support
Name and unit resolution with LOINC mapping
Filesystem logo

Filesystem

Runtime: npxFile Systems
Verified

MCP tools for reading, writing, searching, editing, and managing files within explicitly allowed directories.

Key Features:
Allow-list access control by startup directory arguments
Text, binary, and multi-file reading
Selective edits with dry-run diffs
Webclaw logo

Webclaw

Runtime: npxSearch & Data Extraction

Extracts web pages into markdown, JSON, screenshots, and research-ready context through MCP tools.

Key Features:
Markdown, JSON, text, HTML, and LLM-format extraction
CSS selector and XPath selection
Screenshots, PDF, and MHTML capture
Firecrawl MCP Server logo

Firecrawl MCP Server

Runtime: npxSearch & Data Extraction
Verified

Searches, scrapes, crawls, maps, parses, and monitors web content through Firecrawl MCP tools.

Key Features:
Web, developer, GitHub, and research search
Markdown, HTML, links, screenshots, and JSON extraction
Site mapping and bounded multi-page crawling
Next Devtools MCP logo

Next Devtools MCP

Runtime: npxDeveloper Tools
Verified

Connects coding agents to running Next.js 16+ dev servers for runtime errors, routes, logs, docs, and browser automation guidance.

Key Features:
Discovers running Next.js development servers
Proxies runtime errors, routes, logs, and metadata
Resolves Server Action IDs to source files
Hindsight logo

Hindsight

Runtime: npxKnowledge & Memory

Adds long-term Hindsight memory to agents through retain, recall, and reflect operations.

Key Features:
Long-term agent memory
Retain, recall, and reflect operations
Memory-bank organization

Frequently Asked Questions: Hpo Api Alternatives

The top-rated alternatives to Hpo Api in the Biology & Bioinformatics category include Medical Terminologies MCP, Myatriumhealth MCP, ChemCP. These servers offer complementary or alternative capabilities depending on your deployment stack and authentication requirements.

Hpo Api and its alternatives vary by runtime requirement (Node.js/npx, Python/uvx, Docker, or remote HTTP/SSE endpoints). Check the specification comparison table above to verify command requirements before installing.

It varies by server. Pricing, auth and license are declared by each maintainer and shown in the comparison table where provided — a dash means nothing was declared, so check that project's own site before assuming it's free.

Click the "Compare side-by-side →" button on any alternative card to see an in-depth comparison matrix covering feature lists, stars, npm downloads, install configurations, and schema specifications.