A side-by-side look at the Biopharma Catalyst MCP and Aria MCP Server MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.
Verdict: choose Biopharma Catalyst MCP for biology, medicine and bioinformatics work; choose Aria MCP Server for biology, medicine and bioinformatics as a local process. You can also run both side by side in one mcpServers block.
SEC_USER_AGENT.audit_catalyst, search_clinical_trials, search_pubmed.search_pubmed, search_clinical_trials, search_isrctn.Rows where the two servers differ are marked.
| Spec | ||
|---|---|---|
| Category | Biology, Medicine and Bioinformatics | Biology, Medicine and Bioinformatics |
| Quality signal | 43/100 · Fair | 57/100 · Good |
| Install command | Not confirmed yet | Confirmed |
| Transport | — | Local subprocess (stdio) |
| Auth | Not declared | No auth required |
| Pricing | Not declared | Free |
| Required env vars | SEC_USER_AGENT | None listed |
| Verified owner | Community listing | Community listing |
| GitHub stars | 5 | 3 |
| Directory activity | 1 views 0 installs 0 upvotes | 4 views 0 installs 0 upvotes |
| Tools | 10 | 3 |
| Full listing | View Biopharma Catalyst MCP | View Aria MCP Server |
audit_catalystHeadline tool.** Runs the full Tactical Auditor workflow against (ticker, drug). Deterministic verdict.search_clinical_trialsPipeline + status by intervention; flags terminations, withdrawals, completed-without-readoutsearch_pubmedRecent literature on a drug / mechanism / diseaseget_sec_filingsLast 10 filings (10-K, 10-Q, 8-K, S-1) by tickerget_xbrl_factsCash, quarterly burn, runway months, Going Concern flagget_insider_transactionsRole-classified insider transactions (clinical/financial/admin), coordinated exit detection (72h window), Net Insider Sentiment ($), 10b5-1 detectionget_short_interestShort % of float, days to cover, MoM delta — feeds SHORT_INTEREST_SPIKE and SHORT_SQUEEZE_POTENTIAL signalsget_protocol_snapshotTrial protocol + amendment proximity (goalpost detection)get_market_dataQuote + full options chain (IV, strikes, expirations)get_fda_activityNDA/BLA submissions with decoded status (AP, CRL, WD, etc.); auto-fallback drug→sponsorsearch_pubmedSearch PubMed for peer-reviewed biomedical literature. Read-only operation. No authentication required. Uses NCBI E-utilities public API (rate limit: ~3 requests/sec). Returns up to 10 results per call. No pagination. Returns 'No papers found.' if no results match. Use for: research papers, drug mechanisms, clinical outcomes, disease studies, safety/efficacy data, biomarkers, diagnostics, and any scientific question.search_clinical_trialsSearch ClinicalTrials.gov for clinical studies. Read-only operation. No authentication required. Uses ClinicalTrials.gov v2 public API (no rate limit documented). Returns up to 10 results per call. No pagination. Returns 'No clinical trials found.' if no results match. Use for: active trials, recruiting studies, inclusion/exclusion criteria, phase information, sponsor details, and trial locations.search_isrctnSearch the ISRCTN registry for UK and European clinical trials. Read-only operation. No authentication required. Complements ClinicalTrials.gov by covering trials at UK academic institutions and European research centers not listed on ClinicalTrials.gov. Returns up to 10 results per call, filtered for relevance. Returns 'No ISRCTN trials found.' if no results match. Use for: UK/European trials, academic institution studies, international coverage beyond ClinicalTrials.gov.Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.
No confirmed install command for Biopharma Catalyst MCP yet — follow the setup steps linked from its listing page rather than a guessed package name.
{
"mcpServers": {
"pkotecha-eng-aria-mcp-server": {
"command": "uvx",
"args": [
"aria-mcp-server"
]
}
}
}