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  1. Home
  2. 🧬 Biology & Bioinformatics
  3. Appendix
Appendix logo
Health: ActiveRecent health check succeeded.Last checked 8/10/2026, 11:17:19 PM

Appendix

Enrichment pendingWe haven’t run our AI enrichment pass on this listing yet, so the overview, use cases, and FAQ below may be sparse or missing. We work through the catalog over time β€” check back soon.
View Repository1 GitHub StarsTotal stargazers on GitHub for the source repository (1 stars).Visit Website

Physician-reviewed medical opinions and prescriptions for AI agents.

Quick Install

Automated & IDE Setup

Copy the AI prompt to install this server into Claude Code, Cursor, or another agent β€” or use 1-click editor setup below.

Add to CursorAdd to VS Code
Manual Client & Custom JSON ConfigExpand JSON β–Ύ

Install Config Generator

Choose your client
claude_desktop_config.json
{
  "mcpServers": {
    "appendix": {
      "command": "npx",
      "args": [
        "-y",
        "https://appendix.com"
      ]
    }
  }
}

πŸ’‘ Paste into ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows)

Install Tool Schemas (3) Directory Badge Claim listing Alternatives🧬 More in Biology & Bioinformatics

Capabilities & Tool Schemas (3) ~47 tokensApproximate context cost of this server’s tool schemas (~4 chars/token), before any tool is called. Actual usage depends on your client and model.Self-reported Self-reportedParsed from the repository README, not verified against a live server β€” may be incomplete or out of date.

Inspect callable tools, capabilities, and parameters exposed to AI agents by Appendix.

search_knowledge_base

Search medical literature and treatment guidelines

submit_encounter

Submit a clinical letter for physician review

list_conditions

List available conditions and medications

Documentation Overview

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

Terminal
claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

config.json
{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

ClientURL
Claude Code, Claude Desktop, Claude.ai connectorshttps://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers)https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only β€” the current MCP spec transport (2025-03-26).

Available Tools

ToolDescription
search_knowledge_baseSearch medical literature and treatment guidelines
submit_encounterSubmit a clinical letter for physician review
list_conditionsList available conditions and medications

Development

Terminal
npm install
npm run build
npm start

Watch mode:

Terminal
npm run dev

Environment Variables

VariableDefaultDescription
API_BASE_URLhttps://api.appendix.comAppendix API base URL
PORT3001HTTP listener port

Endpoints

MethodPathPurpose
GET/healthRender health probe
POST GET DELETE/mcpStreamable HTTP transport (stateless mode)

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Frequently Asked Questions about Appendix

Add the following block to your claude_desktop_config.json under mcpServers: "mcpServers": { "appendix": { "command": "npx", "args": ["-y", "Appendix"] } }

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Technical Specs & Signals

Category🧬Biology & Bioinformatics
More technical detailsExpand β–Ύ
TransportSSE (Remote)
RuntimeNode.js
Views0
Unique ViewsTotal visits recorded for this listing page on AllMCPs.
Installs0
Installs & Copy ActionsTotal times users copied install commands or configuration snippets for this server.
GitHub stars1
GitHub Star CountTotal stargazers on GitHub representing community popularity (1 stars).
Last commit2mo ago
Last Repository CommitThe most recent commit or push recorded for this server's GitHub repository.Last commit on Jun 12, 2026
48Quality signal: Fair Β· 48/100How this signal is calculated β–Ύ
Server availabilityNot measured

Not scored for repo-hosted servers β€” we can't reach the running server, only its GitHub page. Hosted MCP endpoints are health-checked live.

Verified ownership10/20
Documentation & tools23/30
Adoption & activity3/15
Community engagement0/10

A guidance signal from public completeness & health data β€” not a user rating. New listings start lower and rise as they add docs, get verified, and grow adoption. Signals we can't observe for a listing are skipped, not counted against it.

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More in 🧬 Biology & Bioinformatics β†’Alternatives to Appendix β†’Install in Claude DesktopInstall in CursorInstall in VS Code