What is the key difference between Uniprot MCP and Biorobotics?

Uniprot MCP belongs to the Biology, Medicine and Bioinformatics category with local stdio execution, while Biorobotics belongs to the Biology, Medicine and Bioinformatics category with local stdio execution.

How do I install Uniprot MCP or Biorobotics in Claude Desktop or Cursor?

Copy the mcpServers JSON configuration snippet provided on this page into your claude_desktop_config.json or ~/.cursor/mcp.json file and restart your AI client.

Are Uniprot MCP and Biorobotics free or paid?

Uniprot MCP operates under a Free / Open Source model (No auth required). Biorobotics operates under a Free / Open Source model (No auth required).

Which MCP server has more tools and community activity?

Uniprot MCP lists 41 tools with 3 views and 3 GitHub stars. Biorobotics lists 6 tools with 4 views and 0 GitHub stars.

Can I use both Uniprot MCP and Biorobotics together in the same MCP host?

Yes! MCP hosts like Claude Desktop, Cursor, Windsurf, Cline, and VS Code support configuring multiple servers under the mcpServers object simultaneously.

Side-by-Side Model Context Protocol Comparison

Uniprot MCP vs Biorobotics

In-depth architectural comparison of the Uniprot MCP and Biorobotics MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

At a Glance & Executive Verdict

Uniprot MCP

Biology, Medicine and Bioinformatics · Local stdio

Quality: 60/100 (Good) | Auth: No auth required

Biorobotics

Biology, Medicine and Bioinformatics · Local stdio

Quality: 48/100 (Fair) | Auth: No auth required

Verdict Summary: Choose Uniprot MCP if you need specialized Biology, Medicine and Bioinformatics tools running via a local process. Choose Biorobotics if your workspace requires Biology, Medicine and Bioinformatics integration with local subprocess execution. Both servers can be configured concurrently in your client's mcpServers manifest.

Which MCP Server Should You Choose?

Choose Uniprot MCP when:

You need dedicated capabilities in the Biology, Medicine and Bioinformatics domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
You have access to required keys: UNIPROT_MCP_CACHE_DIR.
Primary tools included: uniprot_get_entry, uniprot_search, uniprot_get_sequence.

Explore Uniprot MCP Details

Choose Biorobotics when:

You need dedicated capabilities in the Biology, Medicine and Bioinformatics domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
Primary tools included: fetch_genomic_data, resolve_biotech_spatial_intent, map_plate_coordinate.

Feature & Specification Comparison

Specification	Uniprot MCP smaniches Biology, Medicine and Bioinformatics	Biorobotics SEOSiri-Official Biology, Medicine and Bioinformatics
Summary	Auditable UniProt MCP server: 41 tools over the UniProt knowledgebase (entries, features, variants, PTMs, GO terms, cross-references) with per-query SHA-256 provenance and offline replay. uvx uniprot-mcp-server	A stateless, deterministic Bio-Robotics Core Engine converting biological data (UniProt API) to Cartesian G-code coordinates using the Model Context Protocol. 🐍 🏠 🍎 🪟 🐧
Category & Scope

Tools & Capabilities Breakdown

Uniprot MCP Tools (41)

uniprot_get_entry

Fetch a UniProt protein entry by accession (e.g. P04637 for p53, P38398 for BRCA1). Returns function, gene, organism, disease associations, cross-references.

uniprot_search

The general-purpose entry point for finding UniProtKB proteins by any combination of gene, organism, keyword, or free text. Use this first when you don't already have an accession; use ``uniprot_get_entry`` once you do. Examples: '(gene:TP53) AND (organism_id:9606)', 'kinase AND reviewed:true'. ``reviewed_only`` and ``organism`` are convenience shortcuts equivalent to adding the corresponding clause to ``query`` yourself.

uniprot_get_sequence

Fetch the canonical protein sequence in FASTA format. Use this when you need the raw residue string itself (e.g. for local sequence analysis); for pre-computed chemistry derived from this same sequence (molecular weight, pI, hydrophobicity) call ``uniprot_compute_properties`` instead, which fetches the FASTA internally so you don't have to parse it yourself. Always returns markdown/plain-text FASTA — there is no ``response_format`` parameter because FASTA is already the interchange format.

uniprot_get_features

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

Uniprot MCP Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "smaniches-uniprot-mcp": {
      "command": "uvx",
      "args": [
        "uniprot-mcp-server"
      ],
      "env": {
        "UNIPROT_MCP_CACHE_DIR": "YOUR_UNIPROT_MCP_CACHE_DIR_HERE"
      }
    }
  }
}

Biorobotics Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "seosiri-official-biorobotics": {
      "command": "npx",
      "args": [
        "-y",
        "seosiri-official-biorobotics"
      ]
    }
  }
}

Frequently Asked Questions

Uniprot MCP is categorized under Biology, Medicine and Bioinformatics and uses a local stdio subprocess. In contrast, Biorobotics belongs to Biology, Medicine and Bioinformatics using local stdio subprocess. Select Uniprot MCP when you need capabilities focused on biology, medicine and bioinformatics and Biorobotics when you require tools for biology, medicine and bioinformatics.

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