Folklore Clinical Variant Interpretation MCP vs Taiwan Health MCP
A side-by-side look at the Folklore Clinical Variant Interpretation MCP and Taiwan Health MCP MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.
Verdict: choose Folklore Clinical Variant Interpretation MCP for biology & bioinformatics work over a hosted endpoint; choose Taiwan Health MCP for biology & bioinformatics. You can also run both side by side in one mcpServers block.
Which MCP server should you choose?
Choose Folklore Clinical Variant Interpretation MCP when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer a remote HTTP/SSE transport.
- Its auth model fits you: No auth required.
- You want tools like
search_variant_evidence, search_variant_literature, get_publication_details.
Choose Taiwan Health MCP when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- Its auth model fits you: No auth required.
- You have the keys it needs:
POSTGRES_PASSWORD. - You want tools like
health_check, calculate_chads2_vasc, calculate_wells_pe.
Feature & specification comparison
Rows where the two servers differ are marked.
| Spec | ||
|---|---|---|
| Category | Biology & Bioinformatics | Biology & Bioinformatics |
| Quality signal | 79/100 · Great | 60/100 · Good |
| Install command | Confirmed | Not confirmed yet |
| Transport | Remote HTTP/SSE | — |
| Auth | No auth required | No auth required |
| Pricing | Free | Free |
| Required env vars | None listed | POSTGRES_PASSWORD |
| Verified owner | Verified | Community listing |
| GitHub stars | 1 | 167 |
| Directory activity | 8 views 0 installs 0 upvotes | 1 views 0 installs 0 upvotes |
| Tools | 7 | 59 |
| Full listing | View Folklore Clinical Variant Interpretation MCP | View Taiwan Health MCP |
Tools & capabilities
Folklore Clinical Variant Interpretation MCP tools 7
search_variant_evidenceInterpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or interpret pathogenicity, review a VUS, check available ClinVar assertions or population-frequency evidence, or resolve a variant notation. Classify, interpret or resolve one public GRCh38 germline SNV or simple indel smaller than 50 bp. Accepts coordinates, genomic/coding/protein HGVS, SPDI or rsID. Returns normalized variant identity, automated ACMG/AMP decision support, evidence, provenance and explicit limitations. This is variant-level decision support for professional review. It does not evaluate patient context and must not be presented as a diagnosis or treatment recommendation. Never choose a candidate when resolution is ambiguous. Never invent or swap REF/ALT, guess a transcript accession, or relabel another assembly as GRCh38. For reference_mismatch, ask the user to verify the source assembly, position, reference and accession version; preserve the refusal. A bare protein consequence needs a gene or versioned protein accession. A report row may include matching genomic, coding and protein descriptions with a versioned transcript; submit the complete row without discarding conflicting parts. For not_found, preserve the missing exact mapping rather than back-translating a protein change.search_variant_literatureResolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about a variant, gene or associated condition. Associations do not establish causality, pathogenicity or a diagnosis and do not change Folklore's ACMG/AMP classification.get_publication_detailsRetrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, and PubMed/PMC links. Use after literature search when a user asks to inspect a specific publication. This is read-only professional literature evidence and contains no patient context.search_literature_corpusSemantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence and concepts across the corpus. Also accepts genes, variants, phenotypes, HPO and OMIM concepts. Include every known publication identifier in the query when the user asks to compare papers or find work related to a specific paper. Returns source-linked evidence candidates for professional review, not diagnoses, causality claims or treatment recommendations.support_helenaLearn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklore scientific result.get_gene_disease_associationsFind diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance. Preserves conflicting and limited assertions. Gene-disease validity is not variant pathogenicity or a patient diagnosis. Use only a public gene identifier; no patient or case data. Results require professional review.search_disease_genesFind human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source reports and snapshot provenance. Name searches may match multiple diseases; preserve their distinct identities and do not infer a diagnosis. Use only a public disease name or identifier; no symptoms, patient or case data. Results require professional review.
Taiwan Health MCP tools 59
health_checkReturn runtime readiness of the MCP server and every module-backed service. Call this first before any workflow to confirm the required services are online.calculate_chads2_vascCHA₂DS₂-VASc stroke-risk score for non-valvular atrial fibrillation (0–9). Accepts raw age/sex and computes brackets internally; also returns the 2024 ESC CHA₂DS₂-VA adjusted score (sex removed). Decision support only.calculate_wells_peWells criteria for pulmonary embolism (two-tier + three-tier risk). Binary findings are booleans; heart_rate_bpm is raw and the >100 criterion is computed.calculate_wells_dvtWells criteria for deep-vein thrombosis (two-tier + three-tier risk). All items are binary clinical findings.calculate_das28DAS28 rheumatoid arthritis disease activity. formula=esr needs esr (mm/h); formula=crp needs crp (mg/L). Joint counts are 28-joint (0–28); global_health is a 0–100 VAS (not the 0–10 scale CDAI uses). Returns score and activity band (remission/low/moderate/high).calculate_cdaiCDAI (lab-free) rheumatoid arthritis disease activity (0–76). Tender and swollen counts use the 28-joint assessment (0–28 each); patient and provider global assessments are 0–10.calculate_bmiBody mass index with Taiwan (Asian) cutoffs: <18.5 underweight, 18.5–23.9 normal, 24–26.9 overweight, ≥27 obese. Height in cm (not metres), weight in kg.calculate_egfrEstimated glomerular filtration rate using the CKD-EPI 2021 creatinine equation (race-free), adults ≥18 only. serum_creatinine_mgdl in mg/dL (convert µmol/L by dividing by 88.4). Returns eGFR in mL/min/1.73m² and KDIGO CKD stage.calculate_has_bledHAS-BLED bleeding risk on oral anticoagulation (0–9). Accepts raw age (the >65 criterion is computed) and raw systolic BP (the H criterion is computed as SBP >160 mmHg). Returns score and high/low bleeding-risk category (≥3 high).calculate_curb65CURB-65 community-acquired pneumonia severity (0–5). BUN in mg/dL (threshold >19), respiratory rate ≥30, hypotension SBP<90 or DBP≤60, confusion, age ≥65.calculate_qsofaqSOFA sepsis screening (0–3): respiratory rate ≥22, altered mentation (GCS <15), systolic BP ≤100. ≥2 suggests sepsis and further evaluation.calculate_gcsGlasgow Coma Scale (3–15). eye_response 1–4, verbal_response 1–5, motor_response 1–6. Returns total, E/V/M sub-scores, and mild/moderate/severe severity (≤8 severe).- +47 more on the listing page
Ready-to-paste client configs
Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.
Folklore Clinical Variant Interpretation MCP
{
"mcpServers": {
"folklore-clinical-variant-interpretation-mcp": {
"url": "https://api.helena.bio/folklore/v1/mcp"
}
}
}
Taiwan Health MCP
No confirmed install command for Taiwan Health MCP yet — follow the setup steps linked from its listing page rather than a guessed package name.