Folklore Clinical Variant Interpretation MCP vs Taiwan Health MCP

A side-by-side look at the Folklore Clinical Variant Interpretation MCP and Taiwan Health MCP MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.

Folklore Clinical Variant Interpretation MCP logoFolklore Clinical Variant Interpretation MCPBiology & Bioinformatics · Remote HTTP/SSEFolklore MCP 1.5.0 is Helena Bioinformatics’ public, read-only bioinformatics MCP for genomic variant interpretation, ClinGen gene-disease evidence and literature. Seven tools include get_gene_disease_associations (gene symbol/HGNC ID to diseases) and search_disease_genes (MONDO ID/disease name to genes), preserving inheritance, source classifications and provenance. Existing GRCh38 germline variant and literature tools remain available, alongside the optional support_helena helper. Streamable HTTP; no account or API key. No patient data, raw DNA/VCF ingestion or batch processing. Results require professional review and are not diagnoses.79GreatAuth: no auth requiredTaiwan Health MCP logoTaiwan Health MCPBiology & Bioinformatics讓 AI agent 讀懂台灣醫療:63 個 MCP 工具,涵蓋 FHIR R4 / TW Core 驗證、ICD-10、SNOMED CT、LOINC、TFDA 藥品與臨床計算器。MCP server for Taiwan healthcare data.60GoodAuth: no auth required

Verdict: choose Folklore Clinical Variant Interpretation MCP for biology & bioinformatics work over a hosted endpoint; choose Taiwan Health MCP for biology & bioinformatics. You can also run both side by side in one mcpServers block.

Which MCP server should you choose?

Folklore Clinical Variant Interpretation MCP logoChoose Folklore Clinical Variant Interpretation MCP when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • You prefer a remote HTTP/SSE transport.
  • Its auth model fits you: No auth required.
  • You want tools like search_variant_evidence, search_variant_literature, get_publication_details.
Explore Folklore Clinical Variant Interpretation MCP

Taiwan Health MCP logoChoose Taiwan Health MCP when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • Its auth model fits you: No auth required.
  • You have the keys it needs: POSTGRES_PASSWORD.
  • You want tools like health_check, calculate_chads2_vasc, calculate_wells_pe.
Explore Taiwan Health MCP

Feature & specification comparison

Rows where the two servers differ are marked.

SpecFolklore Clinical Variant Interpretation MCP logoFolklore Clinical Variant Interpretation MCPTaiwan Health MCP logoTaiwan Health MCP
CategoryBiology & BioinformaticsBiology & Bioinformatics
Quality signal79/100 · Great60/100 · Good
Install commandConfirmedNot confirmed yet
TransportRemote HTTP/SSE—
AuthNo auth requiredNo auth required
PricingFreeFree
Required env varsNone listedPOSTGRES_PASSWORD
Verified owner VerifiedCommunity listing
GitHub stars1167
Directory activity 8 views 0 installs 0 upvotes 1 views 0 installs 0 upvotes
Tools759

Tools & capabilities

Folklore Clinical Variant Interpretation MCP tools 7

  • search_variant_evidenceInterpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or interpret pathogenicity, review a VUS, check available ClinVar assertions or population-frequency evidence, or resolve a variant notation. Classify, interpret or resolve one public GRCh38 germline SNV or simple indel smaller than 50 bp. Accepts coordinates, genomic/coding/protein HGVS, SPDI or rsID. Returns normalized variant identity, automated ACMG/AMP decision support, evidence, provenance and explicit limitations. This is variant-level decision support for professional review. It does not evaluate patient context and must not be presented as a diagnosis or treatment recommendation. Never choose a candidate when resolution is ambiguous. Never invent or swap REF/ALT, guess a transcript accession, or relabel another assembly as GRCh38. For reference_mismatch, ask the user to verify the source assembly, position, reference and accession version; preserve the refusal. A bare protein consequence needs a gene or versioned protein accession. A report row may include matching genomic, coding and protein descriptions with a versioned transcript; submit the complete row without discarding conflicting parts. For not_found, preserve the missing exact mapping rather than back-translating a protein change.
  • search_variant_literatureResolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about a variant, gene or associated condition. Associations do not establish causality, pathogenicity or a diagnosis and do not change Folklore's ACMG/AMP classification.
  • get_publication_detailsRetrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, and PubMed/PMC links. Use after literature search when a user asks to inspect a specific publication. This is read-only professional literature evidence and contains no patient context.
  • search_literature_corpusSemantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence and concepts across the corpus. Also accepts genes, variants, phenotypes, HPO and OMIM concepts. Include every known publication identifier in the query when the user asks to compare papers or find work related to a specific paper. Returns source-linked evidence candidates for professional review, not diagnoses, causality claims or treatment recommendations.
  • support_helenaLearn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklore scientific result.
  • get_gene_disease_associationsFind diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance. Preserves conflicting and limited assertions. Gene-disease validity is not variant pathogenicity or a patient diagnosis. Use only a public gene identifier; no patient or case data. Results require professional review.
  • search_disease_genesFind human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source reports and snapshot provenance. Name searches may match multiple diseases; preserve their distinct identities and do not infer a diagnosis. Use only a public disease name or identifier; no symptoms, patient or case data. Results require professional review.

Taiwan Health MCP tools 59

  • health_checkReturn runtime readiness of the MCP server and every module-backed service. Call this first before any workflow to confirm the required services are online.
  • calculate_chads2_vascCHA₂DS₂-VASc stroke-risk score for non-valvular atrial fibrillation (0–9). Accepts raw age/sex and computes brackets internally; also returns the 2024 ESC CHA₂DS₂-VA adjusted score (sex removed). Decision support only.
  • calculate_wells_peWells criteria for pulmonary embolism (two-tier + three-tier risk). Binary findings are booleans; heart_rate_bpm is raw and the >100 criterion is computed.
  • calculate_wells_dvtWells criteria for deep-vein thrombosis (two-tier + three-tier risk). All items are binary clinical findings.
  • calculate_das28DAS28 rheumatoid arthritis disease activity. formula=esr needs esr (mm/h); formula=crp needs crp (mg/L). Joint counts are 28-joint (0–28); global_health is a 0–100 VAS (not the 0–10 scale CDAI uses). Returns score and activity band (remission/low/moderate/high).
  • calculate_cdaiCDAI (lab-free) rheumatoid arthritis disease activity (0–76). Tender and swollen counts use the 28-joint assessment (0–28 each); patient and provider global assessments are 0–10.
  • calculate_bmiBody mass index with Taiwan (Asian) cutoffs: <18.5 underweight, 18.5–23.9 normal, 24–26.9 overweight, ≥27 obese. Height in cm (not metres), weight in kg.
  • calculate_egfrEstimated glomerular filtration rate using the CKD-EPI 2021 creatinine equation (race-free), adults ≥18 only. serum_creatinine_mgdl in mg/dL (convert µmol/L by dividing by 88.4). Returns eGFR in mL/min/1.73m² and KDIGO CKD stage.
  • calculate_has_bledHAS-BLED bleeding risk on oral anticoagulation (0–9). Accepts raw age (the >65 criterion is computed) and raw systolic BP (the H criterion is computed as SBP >160 mmHg). Returns score and high/low bleeding-risk category (≥3 high).
  • calculate_curb65CURB-65 community-acquired pneumonia severity (0–5). BUN in mg/dL (threshold >19), respiratory rate ≥30, hypotension SBP<90 or DBP≤60, confusion, age ≥65.
  • calculate_qsofaqSOFA sepsis screening (0–3): respiratory rate ≥22, altered mentation (GCS <15), systolic BP ≤100. ≥2 suggests sepsis and further evaluation.
  • calculate_gcsGlasgow Coma Scale (3–15). eye_response 1–4, verbal_response 1–5, motor_response 1–6. Returns total, E/V/M sub-scores, and mild/moderate/severe severity (≤8 severe).
  • +47 more on the listing page

Ready-to-paste client configs

Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.

Folklore Clinical Variant Interpretation MCP

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "folklore-clinical-variant-interpretation-mcp": {
      "url": "https://api.helena.bio/folklore/v1/mcp"
    }
  }
}

Taiwan Health MCP

No confirmed install command for Taiwan Health MCP yet — follow the setup steps linked from its listing page rather than a guessed package name.

Frequently asked questions

Folklore Clinical Variant Interpretation MCP is categorized under Biology & Bioinformatics and uses a remote HTTP/SSE transport. Taiwan Health MCP belongs to Biology & Bioinformatics and uses an install path we have not confirmed yet. Pick Folklore Clinical Variant Interpretation MCP for biology & bioinformatics work and Taiwan Health MCP for biology & bioinformatics.

Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client. Taiwan Health MCP has no confirmed install command yet — follow its own setup instructions.

Folklore Clinical Variant Interpretation MCP is listed as free. Auth: no auth required. Taiwan Health MCP is listed as free. Auth: no auth required. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.

Yes. MCP clients support multiple servers: add folklore-clinical-variant-interpretation-mcp and taiwan-health-mcp as separate keys in the same mcpServers object, and your assistant will call tools from either one.

On AllMCPs, Folklore Clinical Variant Interpretation MCP has a quality signal of 79/100 (Great) with 8 views, 0 installs and 1 GitHub stars. Taiwan Health MCP has 60/100 (Good) with 1 views, 0 installs and 167 GitHub stars.