Onekgpd MCP vs Ensembl MCP Server
A side-by-side look at the Onekgpd MCP and Ensembl MCP Server MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.
Verdict: choose Onekgpd MCP for biology & bioinformatics work over a hosted endpoint; choose Ensembl MCP Server for biology & bioinformatics as a local process. You can also run both side by side in one mcpServers block.
Which MCP server should you choose?
Choose Onekgpd MCP when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer a remote HTTP/SSE transport.
- Its auth model fits you: No auth required.
Choose Ensembl MCP Server when
- You need dedicated capabilities in the Biology & Bioinformatics domain.
- You prefer a local stdio subprocess transport.
- You want tools like
ensembl_list_species, ensembl_lookup_gene, ensembl_get_sequence.
Feature & specification comparison
Rows where the two servers differ are marked.
| Spec | ||
|---|---|---|
| Category | Biology & Bioinformatics | Biology & Bioinformatics |
| Quality signal | 41/100 · Fair | 57/100 · Good |
| Install command | Confirmed | Confirmed |
| Transport | Remote HTTP/SSE | Local subprocess (stdio) |
| Auth | No auth required | Not declared |
| Pricing | Free | Not declared |
| Required env vars | None listed | None listed |
| Verified owner | Community listing | Community listing |
| GitHub stars | 2 | 3 |
| Directory activity | 2 views 0 installs 0 upvotes | 1 views 0 installs 0 upvotes |
| Tools | Not listed | 7 |
| Full listing | View Onekgpd MCP | View Ensembl MCP Server |
Tools & capabilities
Onekgpd MCP tools
No tool names declared yet. Check the project README from the listing page.
Ensembl MCP Server tools 7
ensembl_list_speciesList species supported by Ensembl with display name, common name, assembly, taxon ID, and divisionensembl_lookup_geneResolve a gene by symbol (synonyms and former symbols included) + species or by stable ID to its Ensembl ID, genomic location, biotype, and transcript listensembl_get_sequenceFetch the DNA, cDNA, CDS, or protein sequence for a gene, transcript, protein, or genomic regionensembl_query_regionFind genomic features (genes, transcripts, variants, regulatory elements, exons) overlapping a chromosomal regionensembl_predict_variantPredict functional consequences of a sequence variant using the Ensembl Variant Effect Predictor (VEP)ensembl_get_homologyFind orthologs and/or paralogs of a gene across species with percent identity and taxonomy levelensembl_get_xrefsRetrieve cross-database references for a gene — HGNC, UniProt, EntrezGene, OMIM, RefSeq, Reactome, and others
Ready-to-paste client configs
Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.
Onekgpd MCP
{
"mcpServers": {
"dnaerys-onekgpd-mcp": {
"url": "http://db.dnaerys.org/mcp"
}
}
}
Ensembl MCP Server
{
"mcpServers": {
"ensembl-mcp-server": {
"command": "bunx",
"args": [
"@cyanheads/ensembl-mcp-server@latest"
]
}
}
}
Frequently asked questions
Onekgpd MCP is categorized under Biology & Bioinformatics and uses a remote HTTP/SSE transport. Ensembl MCP Server belongs to Biology & Bioinformatics and uses a local stdio subprocess. Pick Onekgpd MCP for biology & bioinformatics work and Ensembl MCP Server for biology & bioinformatics.
Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client.
Onekgpd MCP is listed as free. Auth: no auth required. Ensembl MCP Server has no declared pricing — check the project's own site. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.
Yes. MCP clients support multiple servers: add dnaerys-onekgpd-mcp and ensembl-mcp-server as separate keys in the same mcpServers object, and your assistant will call tools from either one.
On AllMCPs, Onekgpd MCP has a quality signal of 41/100 (Fair) with 2 views, 0 installs and 2 GitHub stars. Ensembl MCP Server has 57/100 (Good) with 1 views, 0 installs and 3 GitHub stars.