A side-by-side look at the Clinicaltrialsgov MCP Server and Decoder 3am MCP MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.
Verdict: choose Clinicaltrialsgov MCP Server for biology, medicine and bioinformatics work as a local process; choose Decoder 3am MCP for biology, medicine and bioinformatics over a hosted endpoint. You can also run both side by side in one mcpServers block.
clinicaltrials_search_studies, clinicaltrials_get_study_record, clinicaltrials_get_study_count.classify_sleep_cause, get_cause_info, list_causes.Rows where the two servers differ are marked.
| Spec | ||
|---|---|---|
| Category | Biology, Medicine and Bioinformatics | Biology, Medicine and Bioinformatics |
| Quality signal | 61/100 · Good | 52/100 · Good |
| Install command | Confirmed | Confirmed |
| Transport | Local subprocess (stdio) | Remote HTTP/SSE |
| Auth | Not declared | No auth required |
| Pricing | Not declared | Free |
| Required env vars | None listed | None listed |
| Verified owner | Community listing | Community listing |
| GitHub stars | 99 | 1 |
| Directory activity | 1 views 0 installs 0 upvotes | 3 views 0 installs 0 upvotes |
| Tools | 7 | 4 |
| Full listing | View Clinicaltrialsgov MCP Server | View Decoder 3am MCP |
clinicaltrials_search_studiesSearch studies with full-text and field-specific queries, status/phase/geographic filters, pagination, sorting, and field selectionclinicaltrials_get_study_recordFetch a single study by NCT ID — full protocol record with optional location/outcome/reference capsclinicaltrials_get_study_countFast total study count for a query, without fetching dataclinicaltrials_get_field_valuesDiscover valid values for API fields, with per-value study countsclinicaltrials_get_field_definitionsResolve valid field names — keyword search, path drill-down, or top-level overviewclinicaltrials_get_study_resultsFetch posted results — outcomes, adverse events, participant flow, baseline — for completed studiesclinicaltrials_find_eligibleMatch patient demographics and conditions to candidate recruiting trials, without checking inclusion/exclusion criteriaclassify_sleep_causeClassify the likely primary cause of sleep disruption from a symptom description.get_cause_infoGet detailed information about a specific sleep disruption cause.list_causesList all 5 sleep disruption causes with summaries.get_decoder_urlGet a tracked URL to the full interactive 3AM Decoder.Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.
{
"mcpServers": {
"clinicaltrialsgov-mcp-server": {
"command": "bunx",
"args": [
"clinicaltrialsgov-mcp-server@latest"
]
}
}
}
{
"mcpServers": {
"thelongevityvault-decoder-3am-mcp": {
"url": "https://decoder-3am--thelongevityvault.run.tools/sse"
}
}
}