ChemCP vs Interpro

A side-by-side look at the ChemCP and Interpro MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.

ChemCP logoChemCPBiology & Bioinformatics · Local subprocess (stdio)MCP App that renders 2D molecular structures from SMILES using RDKit.js40FairAuth: not declaredInterpro logoInterproBiology & Bioinformatics · Local subprocess (stdio)InterPro MCP (EBI) — protein family / domain / functional-site classification.53GoodAuth: not declared

Verdict: choose ChemCP for biology & bioinformatics work as a local process; choose Interpro for biology & bioinformatics as a local process. You can also run both side by side in one mcpServers block.

Which MCP server should you choose?

ChemCP logoChoose ChemCP when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • You prefer a local stdio subprocess transport.
Explore ChemCP

Interpro logoChoose Interpro when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • You prefer a local stdio subprocess transport.
  • You want tools like search_entries, get_entry, entries_for_protein.
Explore Interpro

Feature & specification comparison

Rows where the two servers differ are marked.

SpecChemCP logoChemCPInterpro logoInterpro
CategoryBiology & BioinformaticsBiology & Bioinformatics
Quality signal40/100 · Fair53/100 · Good
Install commandConfirmedConfirmed
TransportLocal subprocess (stdio)Local subprocess (stdio)
AuthNot declaredNot declared
PricingNot declaredNot declared
Required env varsNone listedNone listed
Verified ownerCommunity listingCommunity listing
GitHub stars20
Directory activity 1 views 0 installs 0 upvotes 0 views 0 installs 0 upvotes
ToolsNot listed3

Tools & capabilities

ChemCP tools

No tool names declared yet. Check the project README from the listing page.

Interpro tools 3

  • search_entriesSearch InterPro for protein families, domains, repeats and functional sites by keyword (text search over entry names/accessions). InterPro is EBI's integrated protein-signature classification (Pfam, PROSITE, SMART, CDD, PANTHER, ...). Returns matching entries with accession (IPRxxxxxx), name, type…
  • get_entryGet full details for a single InterPro entry by accession (e.g. "IPR000001"). Returns the entry name, type, a plain-text description, member-signature/protein counters, and associated GO terms (molecular function / biological process / cellular component). Use after search_entries or entries_for_pr…
  • entries_for_proteinList all InterPro entries (families, domains, sites) found on a given UniProt protein, by UniProt accession (e.g. "P12345"). Returns each matching InterPro signature with accession, name and type. Useful to functionally annotate a protein. Complements UniProt/AlphaFold. Keyless.

Ready-to-paste client configs

Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.

ChemCP

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "chemcp": {
      "command": "npx",
      "args": [
        "-y",
        "cloudflared"
      ]
    }
  }
}

Interpro

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "interpro": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-interpro"
      ]
    }
  }
}

Frequently asked questions

ChemCP is categorized under Biology & Bioinformatics and uses a local stdio subprocess. Interpro belongs to Biology & Bioinformatics and uses a local stdio subprocess. Pick ChemCP for biology & bioinformatics work and Interpro for biology & bioinformatics.

Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client.

ChemCP has no declared pricing — check the project's own site. Interpro has no declared pricing — check the project's own site. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.

Yes. MCP clients support multiple servers: add chemcp and interpro as separate keys in the same mcpServers object, and your assistant will call tools from either one.

On AllMCPs, ChemCP has a quality signal of 40/100 (Fair) with 1 views, 0 installs and 2 GitHub stars. Interpro has 53/100 (Good) with 0 views, 0 installs and 0 GitHub stars.