Cbioportal vs ChemCP

A side-by-side look at the Cbioportal and ChemCP MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.

Cbioportal logoCbioportalBiology & Bioinformatics · Local subprocess (stdio)cBioPortal MCP — cancer genomics portal.59GoodAuth: no auth requiredChemCP logoChemCPBiology & Bioinformatics · Local subprocess (stdio)MCP App that renders 2D molecular structures from SMILES using RDKit.js40FairAuth: not declared

Verdict: choose Cbioportal for biology & bioinformatics work as a local process; choose ChemCP for biology & bioinformatics as a local process. You can also run both side by side in one mcpServers block.

Which MCP server should you choose?

Cbioportal logoChoose Cbioportal when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • You prefer a local stdio subprocess transport.
  • Its auth model fits you: No auth required.
  • You want tools like search_studies, get_study, get_gene.
Explore Cbioportal

ChemCP logoChoose ChemCP when

  • You need dedicated capabilities in the Biology & Bioinformatics domain.
  • You prefer a local stdio subprocess transport.
Explore ChemCP

Feature & specification comparison

Rows where the two servers differ are marked.

SpecCbioportal logoCbioportalChemCP logoChemCP
CategoryBiology & BioinformaticsBiology & Bioinformatics
Quality signal59/100 · Good40/100 · Fair
Install commandConfirmedConfirmed
TransportLocal subprocess (stdio)Local subprocess (stdio)
AuthNo auth requiredNot declared
PricingFreeNot declared
Required env varsNone listedNone listed
Verified ownerCommunity listingCommunity listing
GitHub stars02
Directory activity 2 views 0 installs 0 upvotes 1 views 0 installs 0 upvotes
Tools4Not listed

Tools & capabilities

Cbioportal tools 4

  • search_studiesSearch public cancer genomics studies in cBioPortal (TCGA, CPTAC, MSK, etc.) by keyword. Matches study name, study id, or cancer-type id (case-insensitive). Returns study ids, names, cancer types, and sample counts. Keyless, open data.
  • get_studyGet full details for one cBioPortal cancer study by its study id (e.g. "brca_tcga_pub", "glioma_mskcc_2019"), including description, cancer type, sample count, PMID, and citation.
  • get_geneResolve a gene to its Entrez gene id and canonical info via cBioPortal. Accepts a HUGO symbol (e.g. "TP53", "BRCA1") or an Entrez gene id. Returns entrez_gene_id, symbol, and type.
  • list_cancer_typesList cancer types defined in cBioPortal (id, display name, parent type). Useful for resolving cancer-type ids used by studies.

ChemCP tools

No tool names declared yet. Check the project README from the listing page.

Ready-to-paste client configs

Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.

Cbioportal

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "cbioportal": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-cbioportal"
      ]
    }
  }
}

ChemCP

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "chemcp": {
      "command": "npx",
      "args": [
        "-y",
        "cloudflared"
      ]
    }
  }
}

Frequently asked questions

Cbioportal is categorized under Biology & Bioinformatics and uses a local stdio subprocess. ChemCP belongs to Biology & Bioinformatics and uses a local stdio subprocess. Pick Cbioportal for biology & bioinformatics work and ChemCP for biology & bioinformatics.

Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client.

Cbioportal is listed as free. Auth: no auth required. ChemCP has no declared pricing — check the project's own site. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.

Yes. MCP clients support multiple servers: add cbioportal and chemcp as separate keys in the same mcpServers object, and your assistant will call tools from either one.

On AllMCPs, Cbioportal has a quality signal of 59/100 (Good) with 2 views, 0 installs and 0 GitHub stars. ChemCP has 40/100 (Fair) with 1 views, 0 installs and 2 GitHub stars.