What is the key difference between Alphafold and Cbioportal?

Alphafold belongs to the Biology & Bioinformatics category with local stdio execution, while Cbioportal belongs to the Biology & Bioinformatics category with local stdio execution.

How do I install Alphafold or Cbioportal in Claude Desktop or Cursor?

Copy the mcpServers JSON configuration snippet provided on this page into your claude_desktop_config.json or ~/.cursor/mcp.json file and restart your AI client.

Are Alphafold and Cbioportal free or paid?

Alphafold operates under a Free / Open Source model (No auth required). Cbioportal operates under a Free / Open Source model (No auth required).

Which MCP server has more tools and community activity?

Alphafold lists 1 tools with 0 views and 0 GitHub stars. Cbioportal lists 0 tools with 0 views and 0 GitHub stars.

Can I use both Alphafold and Cbioportal together in the same MCP host?

Yes! MCP hosts like Claude Desktop, Cursor, Windsurf, Cline, and VS Code support configuring multiple servers under the mcpServers object simultaneously.

Side-by-Side Model Context Protocol Comparison

Alphafold vs Cbioportal

In-depth architectural comparison of the Alphafold and Cbioportal MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

At a Glance & Executive Verdict

Alphafold

Biology & Bioinformatics · Local stdio

Quality: 43/100 (Fair) | Auth: No auth required

Cbioportal

Biology & Bioinformatics · Local stdio

Quality: 27/100 (Emerging) | Auth: No auth required

Verdict Summary: Choose Alphafold if you need specialized Biology & Bioinformatics tools running via a local process. Choose Cbioportal if your workspace requires Biology & Bioinformatics integration with local subprocess execution. Both servers can be configured concurrently in your client's mcpServers manifest.

Which MCP Server Should You Choose?

Choose Alphafold when:

You need dedicated capabilities in the Biology & Bioinformatics domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
Primary tools included: prediction.

Explore Alphafold Details

Choose Cbioportal when:

You need dedicated capabilities in the Biology & Bioinformatics domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).

Explore Cbioportal Details

Feature & Specification Comparison

Specification	A Alphafold Biology & Bioinformatics	Cbioportal Biology & Bioinformatics
Summary	AlphaFold DB MCP — predicted protein structures.	cBioPortal MCP — cancer genomics portal.
Category & Scope	Biology & Bioinformatics	Biology & Bioinformatics
Quality signal

Tools & Capabilities Breakdown

Alphafold Tools (1)

prediction

Cbioportal Tools (0)

No explicit tool names declared in metadata yet. Check project README on main listing page.

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

Alphafold Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "alphafold": {
      "command": "npx",
      "args": [
        "-y",
        "alphafold"
      ]
    }
  }
}

Cbioportal Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "cbioportal": {
      "command": "npx",
      "args": [
        "-y",
        "cbioportal"
      ]
    }
  }
}

Frequently Asked Questions

Alphafold is categorized under Biology & Bioinformatics and uses a local stdio subprocess. In contrast, Cbioportal belongs to Biology & Bioinformatics using local stdio subprocess. Select Alphafold when you need capabilities focused on biology & bioinformatics and Cbioportal when you require tools for biology & bioinformatics.

More alternatives to Alphafold More alternatives to Cbioportal Biology & Bioinformatics category hub