In-depth architectural comparison of the Pombase and Sgd MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.
At a Glance & Executive Verdict
Pombase
Databases · Remote HTTP/SSE
Quality: 51/100 (Good) | Auth: No auth required
Sgd
Databases · Remote HTTP/SSE
Quality: 48/100 (Fair) | Auth: No auth required
Verdict Summary: Choose Pombase if you need specialized Databases tools running via a hosted cloud SSE transport. Choose Sgd if your workspace requires Databases integration with remote web transport. Both servers can be configured concurrently in your client's mcpServers manifest.
Which MCP Server Should You Choose?
P
Choose Pombase when:
You need dedicated capabilities in the Databases domain.
You prefer remote streaming HTTP/SSE transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
PomBase (fission yeast / S. pombe model-organism DB): look up a gene by its PomBase systematic id and return its product, protein domains (InterPro), deletion viability, UniProt id, and curation status. Keyless. NOTE: requires a systematic id like "SPAC1002.01" or "SPBC2F12.13" — standard gene name…
get_reference
PomBase: look up a curated S. pombe publication by its PubMed id (e.g. "PMID:11739790") and return its title, citation, authors, year, abstract, and how many genes it annotates. Keyless.
Sgd Tools (3)
get_gene
Look up a single yeast (S. cerevisiae) gene/locus in SGD (Saccharomyces Genome Database, the authoritative budding-yeast genetics resource). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns the standard name, systematic name, SGDID,…
search_genes
Search SGD (Saccharomyces Genome Database, the authoritative budding-yeast / S. cerevisiae genetics resource) for genes, loci, alleles, and other entities by free-text query. Returns matching hits with their name, category, and href. Keyless.
Ready-to-Paste Client Configurations
Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).
Pombase is categorized under Databases and uses a remote streaming HTTP/SSE transport. In contrast, Sgd belongs to Databases using remote streaming HTTP/SSE transport. Select Pombase when you need capabilities focused on databases and Sgd when you require tools for databases.
Get Gene Ontology (GO) annotations for a yeast (S. cerevisiae) gene/locus from SGD (Saccharomyces Genome Database). Accepts a systematic name (e.g. YAL001C), a standard gene name (e.g. TFC3), or an SGDID (e.g. S000000001). Returns GO terms with their GO id, aspect (molecular function / biological p…