Open Notebook vs Opentargets

In-depth architectural comparison of the Open Notebook and Opentargets MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

Which MCP Server Should You Choose?

Choose Open Notebook when:

• You need dedicated capabilities in the Developer Tools domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).
• Primary tools included: search_capabilities.

Explore Open Notebook Details

Choose Opentargets when:

• You need dedicated capabilities in the Developer Tools domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).

Explore Opentargets Details

Feature & Specification Comparison

Specification	Open Notebook Developer Tools	Opentargets Developer Tools
Summary	MCP server that wraps the Open Notebook API	Open Targets MCP server for targets, diseases, drugs, variants, and evidence
Category & Scope	Developer Tools	Developer Tools
Quality signal

Tools & Capabilities Breakdown

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

{
  "mcpServers": {
    "open-notebook": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/inspector"
      ]
    }
  }
}

{
  "mcpServers": {
    "opentargets": {
      "command": "uvx",
      "args": [
        "--from"
      ]
    }
  }
}

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