Obsidian Brain vs Enzyme

In-depth architectural comparison of the Obsidian Brain and Enzyme MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

Which MCP Server Should You Choose?

O

Choose Obsidian Brain when:

• You need dedicated capabilities in the Knowledge & Memory domain.
• You prefer local stdio subprocess transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).

Explore Obsidian Brain Details

Choose Enzyme when:

• You need dedicated capabilities in the Knowledge & Memory domain.
• You prefer remote streaming HTTP/SSE transport architecture.
• Your security boundary fits: No auth required (Free / Open Source).

Explore Enzyme Details

Feature & Specification Comparison

Specification	O Obsidian Brain Knowledge & Memory	Enzyme Knowledge & Memory
Summary	Obsidian MCP server: semantic search, knowledge graph, and vault editing. No plugin required.	Semantic search and pattern discovery for Obsidian and markdown vaults.
Category & Scope	Knowledge & Memory	Knowledge & Memory
Quality signal

Tools & Capabilities Breakdown

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

{
  "mcpServers": {
    "obsidian-brain": {
      "command": "npx",
      "args": [
        "-y",
        "cache"
      ]
    }
  }
}

{
  "mcpServers": {
    "enzyme": {
      "url": "https://img.shields.io/discord/1191288276536008745?label=Discord&logo=discord&style=flat-square)](https://discord.gg/nhvsqtKjQd"
    }
  }
}

Related MCP Server Comparisons