Side-by-Side Model Context Protocol Comparison
Myvariant vs Valet
In-depth architectural comparison of the Myvariant and Valet MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.
At a Glance & Executive Verdict
Myvariant
Developer Tools · Local stdio
Quality: 40/100 (Fair) | Auth: No auth required
Valet
Developer Tools · Local stdio
Quality: 48/100 (Fair) | Auth: No auth required
Verdict Summary: Choose Myvariant if you need specialized Developer Tools tools running via a local process. Choose Valet if your workspace requires Developer Tools integration with local subprocess execution. Both servers can be configured concurrently in your client's
mcpServers manifest.Which MCP Server Should You Choose?
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Choose Myvariant when:
- You need dedicated capabilities in the Developer Tools domain.
- You prefer local stdio subprocess transport architecture.
- Your security boundary fits: No auth required (Free / Open Source).
- Primary tools included: query, variant, metadata.
Choose Valet when:
- You need dedicated capabilities in the Developer Tools domain.
- You prefer local stdio subprocess transport architecture.
- Your security boundary fits: No auth required (Freemium).
Feature & Specification Comparison
Tools & Capabilities Breakdown
Myvariant Tools (3)
query
Search aggregated human genetic-variant annotations on MyVariant.info. Accepts an rsID ("rs58991260"), an HGVS id ("chr1:g.218631822G>A"), or a fielded query ("dbnsfp.genename:CDK2", "clinvar.rcv.clinical_significance:pathogenic"). Each hit merges dbSNP, ClinVar clinical significance, CADD/dbNSFP d…
variant
Get the full merged annotation for a single human genetic variant by its HGVS id (e.g. "chr7:g.140453136A>T"). Returns annotations aggregated from dbSNP, ClinVar (pathogenicity / clinical significance), CADD and dbNSFP (deleteriousness/conservation scores), and gnomAD (population allele frequencies…
metadata
Returns MyVariant.info build metadata: total indexed variant count, available annotation sources (dbSNP, ClinVar, CADD, dbNSFP, gnomAD), and their current release/build versions.
Valet Tools (0)
No explicit tool names declared in metadata yet. Check project README on main listing page.
Ready-to-Paste Client Configurations
Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).
Myvariant Configuration
Valet Configuration