Mydisease vs Myvariant — MCP Server Comparison | AllMCPs
Side-by-Side Model Context Protocol Comparison
Mydisease vs Myvariant
In-depth architectural comparison of the Mydisease and Myvariant MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.
At a Glance & Executive Verdict
Mydisease
Developer Tools · Remote HTTP/SSE
Quality: 45/100 (Fair) | Auth: No auth required
Myvariant
Developer Tools · Remote HTTP/SSE
Quality: 45/100 (Fair) | Auth: No auth required
Verdict Summary: Choose Mydisease if you need specialized Developer Tools tools running via a hosted cloud SSE transport. Choose Myvariant if your workspace requires Developer Tools integration with remote web transport. Both servers can be configured concurrently in your client's mcpServers manifest.
Which MCP Server Should You Choose?
M
Choose Mydisease when:
You need dedicated capabilities in the Developer Tools domain.
You prefer remote streaming HTTP/SSE transport architecture.
Your security boundary fits: No auth required (Free / Open Source).
Search MyDisease.info for diseases by free-text name or fielded query. Returns matching hits, each keyed by a MONDO disease id (e.g. "MONDO:0015967") with the best-matching ontology and annotation keys. Use this to resolve a disease name to canonical ontology ids before calling the "disease" tool.…
disease
Fetch the full aggregated annotation object for a single disease id. Accepts MONDO ("MONDO:0015967"), DOID ("DOID:9351"), OMIM ("OMIM:125853") and other supported ontology ids. Returns cross-referenced data including MONDO ontology (labels, synonyms, xrefs, parents/children), gene-disease associati…
metadata
Returns MyDisease.info build metadata: total disease document count, available annotation sources (MONDO, DOID, OMIM, DisGeNET, HPO, CTD), and their current release versions.
Myvariant Tools (3)
query
Search aggregated human genetic-variant annotations on MyVariant.info. Accepts an rsID ("rs58991260"), an HGVS id ("chr1:g.218631822G>A"), or a fielded query ("dbnsfp.genename:CDK2", "clinvar.rcv.clinical_significance:pathogenic"). Each hit merges dbSNP, ClinVar clinical significance, CADD/dbNSFP d…
Ready-to-Paste Client Configurations
Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).
Mydisease is categorized under Developer Tools and uses a remote streaming HTTP/SSE transport. In contrast, Myvariant belongs to Developer Tools using remote streaming HTTP/SSE transport. Select Mydisease when you need capabilities focused on developer tools and Myvariant when you require tools for developer tools.
Get the full merged annotation for a single human genetic variant by its HGVS id (e.g. "chr7:g.140453136A>T"). Returns annotations aggregated from dbSNP, ClinVar (pathogenicity / clinical significance), CADD and dbNSFP (deleteriousness/conservation scores), and gnomAD (population allele frequencies…
metadata
Returns MyVariant.info build metadata: total indexed variant count, available annotation sources (dbSNP, ClinVar, CADD, dbNSFP, gnomAD), and their current release/build versions.