What is the key difference between Genefoundry and Manifold?

Genefoundry belongs to the Developer Tools category with cloud HTTP/SSE execution, while Manifold belongs to the Developer Tools category with local stdio execution.

How do I install Genefoundry or Manifold in Claude Desktop or Cursor?

Copy the mcpServers JSON configuration snippet provided on this page into your claude_desktop_config.json or ~/.cursor/mcp.json file and restart your AI client.

Are Genefoundry and Manifold free or paid?

Genefoundry operates under a Free / Open Source model (No auth required). Manifold operates under a Free / Open Source model (No auth required).

Which MCP server has more tools and community activity?

Genefoundry lists 0 tools with 0 views and 4 GitHub stars. Manifold lists 0 tools with 0 views and 4 GitHub stars.

Can I use both Genefoundry and Manifold together in the same MCP host?

Yes! MCP hosts like Claude Desktop, Cursor, Windsurf, Cline, and VS Code support configuring multiple servers under the mcpServers object simultaneously.

Side-by-Side Model Context Protocol Comparison

Genefoundry vs Manifold

In-depth architectural comparison of the Genefoundry and Manifold MCP servers. Compare execution transports, security boundaries, tool capabilities, quality scores, and ready-to-paste client installation snippets for Claude, Cursor, Windsurf, and VS Code.

At a Glance & Executive Verdict

Genefoundry

Developer Tools · Remote HTTP/SSE

Quality: 37/100 (Fair) | Auth: No auth required

Manifold

Developer Tools · Local stdio

Quality: 31/100 (Emerging) | Auth: No auth required

Verdict Summary: Choose Genefoundry if you need specialized Developer Tools tools running via a hosted cloud SSE transport. Choose Manifold if your workspace requires Developer Tools integration with local subprocess execution. Both servers can be configured concurrently in your client's mcpServers manifest.

Which MCP Server Should You Choose?

Choose Genefoundry when:

You need dedicated capabilities in the Developer Tools domain.
You prefer remote streaming HTTP/SSE transport architecture.
Your security boundary fits: No auth required (Free / Open Source).

Explore Genefoundry Details

Choose Manifold when:

You need dedicated capabilities in the Developer Tools domain.
You prefer local stdio subprocess transport architecture.
Your security boundary fits: No auth required (Free / Open Source).

Explore Manifold Details

Feature & Specification Comparison

Specification	Genefoundry Developer Tools	Manifold Developer Tools
Summary	MCP gateway federating 21 biomedical MCP servers behind one endpoint: gnomAD, ClinVar, HPO, VEP.	MCP gateway aggregating MCP servers and OpenAPI/Swagger REST APIs behind one MCP endpoint
Category & Scope	Developer Tools	Developer Tools
Quality signal

Tools & Capabilities Breakdown

Genefoundry Tools (0)

No explicit tool names declared in metadata yet. Check project README on main listing page.

Manifold Tools (0)

No explicit tool names declared in metadata yet. Check project README on main listing page.

Ready-to-Paste Client Configurations

Paste either (or both) of these JSON server blocks into your client config file (e.g. claude_desktop_config.json or ~/.cursor/mcp.json).

Genefoundry Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "genefoundry": {
      "url": "https://img.shields.io/badge/python-3.12%2B-3776AB?logo=python&logoColor=white)](https://www.python.org/"
    }
  }
}

Manifold Configuration

mcpServers (Claude Desktop / Cursor)

{
  "mcpServers": {
    "manifold": {
      "command": "npx",
      "args": [
        "-y",
        "manifold"
      ]
    }
  }
}

Frequently Asked Questions

Genefoundry is categorized under Developer Tools and uses a remote streaming HTTP/SSE transport. In contrast, Manifold belongs to Developer Tools using local stdio subprocess. Select Genefoundry when you need capabilities focused on developer tools and Manifold when you require tools for developer tools.

More alternatives to Genefoundry More alternatives to Manifold Developer Tools category hub