Dbx vs Uniprot

A side-by-side look at the Dbx and Uniprot MCP servers: transport, auth, tools, quality signals, and the config to install either one in Claude, Cursor, Windsurf or VS Code.

Dbx logoDbxDatabases · Local subprocess (stdio)Query databases from AI agents using connections configured in DBX.53GoodAuth: not declaredUniprot logoUniprotDatabases · Local subprocess (stdio)UniProt MCP — protein sequence + function database.57GoodAuth: not declared

Verdict: choose Dbx for databases work as a local process; choose Uniprot for databases as a local process. You can also run both side by side in one mcpServers block.

Which MCP server should you choose?

Dbx logoChoose Dbx when

  • You need dedicated capabilities in the Databases domain.
  • You prefer a local stdio subprocess transport.
Explore Dbx

Uniprot logoChoose Uniprot when

  • You need dedicated capabilities in the Databases domain.
  • You prefer a local stdio subprocess transport.
  • You want tools like search, get, proteomes_search.
Explore Uniprot

Feature & specification comparison

Rows where the two servers differ are marked.

SpecDbx logoDbxUniprot logoUniprot
CategoryDatabasesDatabases
Quality signal53/100 · Good57/100 · Good
Install commandConfirmedConfirmed
TransportLocal subprocess (stdio)Local subprocess (stdio)
AuthNot declaredNot declared
PricingFreeNot declared
Required env varsNone listedNone listed
Verified ownerCommunity listingCommunity listing
GitHub stars27,3590
Directory activity 5 views 0 installs 0 upvotes 1 views 0 installs 0 upvotes
ToolsNot listed6

Tools & capabilities

Dbx tools

No tool names declared yet. Check the project README from the listing page.

Uniprot tools 6

  • search"Find protein [name]" / "look up [gene] in UniProt" / "BRCA1 / TP53 / insulin protein info" / "all proteins for [organism]" — UniProtKB search via Lucene-style queries (e.g. gene:BRCA1 AND organism_id:9606 for human BRCA1). UniProt is the authoritative protein-sequence-and-function database — use for protein characterization, function annotation, sequence retrieval, and cross-references to PDB/GO/PubMed.
  • get"Fetch protein [P12345]" / "UniProt entry for [accession]" / "FASTA sequence for [protein]" — single UniProtKB entry by accession (e.g. P12345 or P38398 for BRCA1_HUMAN). Returns full protein record: sequence, function annotations, GO terms, cross-refs, post-translational modifications, variants. Pass format=fasta for sequence only.
  • proteomes_search"Reference proteome for [organism]" / "complete protein set of [species]" — search UniProt reference proteomes (the curated representative protein set per organism). Use as a starting point for genome-scale protein analyses.
  • taxonomy_search"NCBI taxonomy ID for [organism]" / "taxid for [species]" / "look up [Latin name] in NCBI taxonomy" — search NCBI Taxonomy via UniProt's mirror. Returns taxonomic IDs you can use as organism_id filters in `search` (9606 = human, 10090 = mouse, 7227 = D. melanogaster, etc).
  • keyword"UniProt keyword KW-N info" / "what does keyword [X] mean" — fetch a UniProt controlled-vocabulary keyword by ID. Use to look up annotation tags like "Kinase" / "Membrane" / "Disease-associated".
  • feature_summary"Domain map of [protein]" / "annotated features of [accession]" / "what regions / sites does [protein] have" — annotated features (domains, active sites, transmembrane regions, mutagenesis sites, glycosylation, disulfide bonds, etc.) for a UniProt accession. Use for structural/functional analysis without pulling the full protein record.

Ready-to-paste client configs

Paste either block (or both) into your client config, e.g. claude_desktop_config.json or ~/.cursor/mcp.json. We only show a config when the install command is confirmed.

Dbx

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "dbx": {
      "command": "npx",
      "args": [
        "-y",
        "@dbx-app/mcp-server"
      ]
    }
  }
}

Uniprot

mcpServers (Claude Desktop / Cursor)
{
  "mcpServers": {
    "uniprot": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-uniprot"
      ]
    }
  }
}

Frequently asked questions

Dbx is categorized under Databases and uses a local stdio subprocess. Uniprot belongs to Databases and uses a local stdio subprocess. Pick Dbx for databases work and Uniprot for databases.

Copy the mcpServers block from the config section on this page into your client's config (for example claude_desktop_config.json or ~/.cursor/mcp.json), then fully restart the client.

Dbx is listed as free. Uniprot has no declared pricing — check the project's own site. If a server needs environment variables such as API keys, define them under the env key in your client's MCP config.

Yes. MCP clients support multiple servers: add dbx and uniprot as separate keys in the same mcpServers object, and your assistant will call tools from either one.

On AllMCPs, Dbx has a quality signal of 53/100 (Good) with 5 views, 0 installs and 27,359 GitHub stars. Uniprot has 57/100 (Good) with 1 views, 0 installs and 0 GitHub stars.